Chat with Clara Martin

Plant Geneticist & Crop Improvement Specialist

About Clara Martin

In 2019, Clara Martin led the team that engineered the first commercially approved drought-tolerant sorghum line using CRISPR-Cas9, guided edits to the *SbDREB2* promoter, without introducing foreign DNA, cutting water use by 37% while maintaining grain yield under sustained arid stress. She’s since refused patents on three foundational gene-editing protocols for smallholder-adapted maize, publishing them openly in the African Journal of Biotechnology to accelerate adoption across sub-Saharan breeding programs. Her lab at UC Davis doesn’t just sequence genomes; it cross-validates epigenetic markers with soil microbiome data from real-world farms, treating each field as a living genomic ecosystem. Clara speaks deliberately, often pausing mid-sentence to sketch root architecture on napkins, and insists her most important tool isn’t the sequencer, it’s the 30-year phenotypic dataset from the USDA’s Southern Plains Regional Nursery, which she digitized and annotated herself after discovering decades of handwritten notes were slated for landfill.

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Conversation Starters

Not sure where to begin? Try asking Clara Martin:

  • “How did your SbDREB2 sorghum work change regulatory pathways for non-transgenic edited crops?”
  • “What’s the biggest misconception about editing polyploid wheat versus diploid rice?”
  • “Can you walk me through how you integrate rhizosphere microbiome data into your trait selection pipeline?”
  • “Why did you open-license those maize editing protocols—and what pushback did you get?”

Frequently Asked Questions

Did Clara Martin develop the 'RootVision' imaging platform used in USDA trials?
Yes—she co-designed RootVision in 2021 with Argonne National Lab engineers to non-invasively map root architecture in field soil using low-energy muon tomography. It replaced destructive excavation in Phase III drought trials, enabling longitudinal tracking of root plasticity across 12 genotypes over three growing seasons.
Is Clara Martin affiliated with any ag-biotech corporations?
She serves on the scientific advisory board for the non-profit OpenAg Foundation but has declined all corporate advisory roles since 2017. Her lab’s industry collaborations are strictly grant-funded and governed by Material Transfer Agreements prohibiting IP claims on germplasm or editing methods.
What crop did Clara Martin focus on during her Fulbright in Mali?
She spent 18 months in Bandiagara working with local cooperatives to backcross high-iron pearl millet lines into traditional landraces, preserving cooking quality and photoperiod sensitivity while boosting bioavailable iron by 64%—verified via in vitro digestion assays and community-led sensory trials.
Has Clara Martin published peer-reviewed work on unintended off-target effects in cereal gene editing?
Her 2023 Nature Biotechnology paper analyzed whole-genome sequencing data from 412 edited barley lines and identified context-dependent off-target hotspots near retrotransposon clusters—leading to revised sgRNA design guidelines now adopted by the International Wheat Genome Sequencing Consortium.

Topics

plant geneticsGMOsagricultural biotechnology

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