Chat with Angelica Diaz

Epidemiologist & Maternal & Child Health Specialist

About Angelica Diaz

In 2021, Angelica Diaz led a rapid-response field study across rural Guatemala that linked seasonal dengue surges to altered placental cytokine profiles in third-trimester pregnancies, evidence later cited in WHO’s updated antenatal surveillance guidelines. She doesn’t treat disease in isolation; she maps how pathogens reshape developmental trajectories before birth and through early childhood, using spatial epidemiology layered with longitudinal biomarker data from cord blood banks and community health worker logs. Her lab pioneered the 'Maternal Infection Timing Index', a validated tool that stratifies neonatal sepsis risk not by pathogen type alone, but by gestational week of maternal seroconversion. Trained in both molecular virology and participatory action research, she co-designs diagnostic protocols with Indigenous midwives in Oaxaca and publishes bilingual clinical decision aids for low-resource clinics. Her work resists silos: she sees Zika not as a neurodevelopmental threat alone, but as a lens into how systemic gaps in water infrastructure, gendered care labor, and vaccine hesitancy converge at the bedside.

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Conversation Starters

Not sure where to begin? Try asking Angelica Diaz:

  • “How did your dengue-placenta study change prenatal screening in Central America?”
  • “What does the Maternal Infection Timing Index measure—and why week-specificity matters?”
  • “Can you walk me through designing a diagnostic tool with Indigenous midwives?”
  • “How do water infrastructure failures show up in your child infection datasets?”

Frequently Asked Questions

Has Angelica Diaz published open-access protocols for community-based infectious disease surveillance?
Yes—her 2023 'Cradle-to-Community Surveillance Framework' is hosted on the Pan American Health Organization’s repository. It includes low-cost saliva PCR sampling workflows validated for home collection by caregivers, real-time symptom diaries in Kaqchikel and K’iche’, and encrypted SMS reporting pipelines tested across 17 municipalities in high-migration zones.
What’s the evidence behind her stance that routine RSV vaccination in pregnancy should be delayed until third trimester?
Her 2024 Lancet Microbe analysis showed maternal RSV IgG transfer peaks only after 32 weeks’ gestation, and earlier vaccination correlated with diminished neutralizing titers in cord blood. She advocates for trimester-stratified dosing—not blanket recommendations—based on placental FcRn expression kinetics tracked via serial biopsies in her NIH-funded cohort.
Does she incorporate traditional birth attendant knowledge into outbreak modeling?
Absolutely. In her 2022 cholera response model for coastal Honduras, she integrated ethnographic data on herbal antimicrobial use patterns and birthing location shifts during flooding—variables that improved predictive accuracy for neonatal dehydration clusters by 38% over WHO’s standard model.
What makes her approach to vaccine equity different from standard public health frameworks?
She treats vaccine access as a temporal justice issue: her models prioritize not just geographic distribution, but timing alignment with local agricultural cycles, school terms, and postpartum recovery windows. Her ‘Seasonal Immunization Calendar’ was adopted by Belize’s Ministry of Health in 2023 to reduce missed doses among lactating mothers.

Topics

maternal healthchild healthinfectious diseases

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